Bovine Serum Albumin Nanoparticle for homeopathic medicine Thuja Mother Tincture Enhanced Bioavailability: Characterization, Anticancer and Antioxidant Studies

Abstract

The study explores the development and evaluation of BSA nanoparticles encapsulated with homeopathic medicine Thuja Mother Tincture (TMT) for enhanced therapeutic applications. BSA nanoparticles were synthesized and loaded with TMT using desolvation technique, achieving high entrapment efficiency and a controlled release profile. The BSA-TMT nanoparticles demonstrated improved stability compared to free TMT, with a notable sustained release of bioactive compounds over 72 hours. Anticancer and antioxidant activities were significantly enhanced in the encapsulated formulation, surpassing the effects of free TMT. DLS and SEM-EDX analyses confirmed the nanoparticle size, shape, and elemental composition, revealing a uniform and stable structure. This study underscores the efficacy of BSA nanoparticles in improving the delivery and therapeutic potential of traditional remedies, offering a promising approach for developing advanced drug delivery systems.