Red tea and ginger formulation mediated silver nanoparticles and its antioxidant activity.
Keywords:
Antioxidants, Ginger , oxidative stress, Red tea, silver nanoparticles.
Abstract
Background: Poor solubility and bioavailability of herbal drugs, which are a barrier to their effective administration, can be resolved with the use of appropriate nanomaterials that will improve their pharmacokinetics.Aim:The aim of the current study is to analyse the synthesis of silver nanoparticles from red tea and ginger extract and to determine the antioxidant potential of it.Materials and Methods: DPPH free radical scavenging assay and hydroxyl radical scavenging assay was performed to determine the antioxidant potential of red tea and ginger formulation mediated silver nanoparticles. The percentage inhibition of DPPH radical scavenging activity and hydroxyl radical scavenging activity was calculated. The data was analysed statistically and the level of significance was considered at the level of p<0.05.Results: There is a dose-dependent increase in the percentage of inhibition of DPPH free radical and hydroxyl free radical by red tea and ginger formulation mediated silver nanoparticles. The percentage of inhibition increases with increase in the concentration of the extract. Conclusion: The study concludes that red tea and ginger formulation mediated silver nanoparticles have potent antioxidant properties and can be used as an herbal antidote for the treatment of various diseases due to oxidative stress.
References
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2. Egbuna C, Jeevanandam J, Patrick-Iwuanyanwu KC, Onyeike EN. Application of Nanotechnology in Food Science, Processing and Packaging. Springer Nature; 2022. 266 p.
3. Cioffi N, Rai M. Nano-Antimicrobials: Progress and Prospects. Springer Science & Business Media; 2012. 563 p.
4. Prasad R. Fungal Nanotechnology: Applications in Agriculture, Industry, and Medicine. Springer; 2017. 295 p.
5. Alarcon EI, Griffith M, Udekwu KI. Silver Nanoparticle Applications: In the Fabrication and Design of Medical and Biosensing Devices. Springer; 2015. 146 p.
6. Firdhouse MJ, Jannathul Firdhouse M, Lalitha P. Biogenic silver nanoparticles – Synthesis, characterization and its potential against cancer inducing bacteria [Internet]. Vol. 222, Journal of Molecular Liquids. 2016. p. 1041–50. Available from: http://dx.doi.org/10.1016/j.molliq.2016.07.141
7. Jeena K, Liju VB, Kuttan R. Antioxidant, anti-inflammatory and antinociceptive activities of essential oil from ginger. Indian J Physiol Pharmacol. 2013 Jan;57(1):51–62.
8. Kulkarni RA, Deshpande AR. Anti-inflammatory and antioxidant effect of ginger in tuberculosis. J Complement Integr Med. 2016 Jun 1;13(2):201–6.
9. Ghlissi Z, Atheymen R, Boujbiha MA, Sahnoun Z, Makni Ayedi F, Zeghal K, et al. Antioxidant and androgenic effects of dietary ginger on reproductive function of male diabetic rats. Int J Food Sci Nutr. 2013 Dec;64(8):974–8.
10. Wang H. Ginger Cultivation and Its Antimicrobial and Pharmacological Potentials. BoD – Books on Demand; 2020. 164 p.
11. Piek H, Venter I, Rautenbach F, Marnewick JL. Rooibos herbal tea: An optimal cup and its consumers. Health Saf Code Annot State Calif Adopt April 7 1939 Calif. 2019 Feb 21;24:1090.
12. Joubert E, Beelders T, de Beer D, Malherbe CJ, de Villiers AJ, Sigge GO. Variation in Phenolic Content and Antioxidant Activity of Fermented Rooibos Herbal Tea Infusions: Role of Production Season and Quality Grade [Internet]. Vol. 60, Journal of Agricultural and Food Chemistry. 2012. p. 9171–9. Available from: http://dx.doi.org/10.1021/jf302583r
13. Lawal AO, Davids LM, Marnewick JL. Rooibos (Aspalathus linearis) and honeybush (Cyclopia species) modulate the oxidative stress associated injury of diesel exhaust particles in human umbilical vein endothelial cells [Internet]. Vol. 59, Phytomedicine. 2019. p. 152898. Available from: http://dx.doi.org/10.1016/j.phymed.2019.152898
14. Akinfenwa AO, Abdul NS, Marnewick JL, Hussein AA. Protective Effects of Linearthin and Other Chalcone Derivatives from Aspalathus linearis (Rooibos) against UVB Induced Oxidative Stress and Toxicity in Human Skin Cells [Internet]. Vol. 10, Plants. 2021. p. 1936. Available from: http://dx.doi.org/10.3390/plants10091936
15. Marnewick JL, Rautenbach F, Venter I, Neethling H, Blackhurst DM, Wolmarans P, et al. Effects of rooibos (Aspalathus linearis) on oxidative stress and biochemical parameters in adults at risk for cardiovascular disease [Internet]. Vol. 133, Journal of Ethnopharmacology. 2011. p. 46–52. Available from: http://dx.doi.org/10.1016/j.jep.2010.08.061
16. Marnewick JL, Venter I, Rautenbach F, Neethling H, Kotze M. Rooibos: Effect on Iron Status of South African Adults at Risk for Coronary Heart Disease [Internet]. Vol. 53, Free Radical Biology and Medicine. 2012. p. S85. Available from: http://dx.doi.org/10.1016/j.freeradbiomed.2012.10.340
17. Marnewick JL, Venter I, Rautenbach F, Neethling H, Kotze M. Rooibos: Effect on Iron Status in South African Adults at Risk for Coronary Heart Disease [Internet]. ACS Symposium Series. 2013. p. 103–14. Available from: http://dx.doi.org/10.1021/bk-2013-1127.ch008
18. Obasa Z, van Vuuren MA, Huisamen B, Windvogel SL. The modulating effects of green rooibos (Aspalathuslinearis) extract on vascular function and antioxidantstatus in obese Wistar rats [Internet]. Vol. 32, Cardiovascular Journal of Africa. 2021. p. 33–43. Available from: http://dx.doi.org/10.5830/cvja-2020-048
19. Canda BD, Oguntibeju OO, Marnewick JL. Effects of Consumption of Rooibos (Aspalathus linearis) and a Rooibos-Derived Commercial Supplement on Hepatic Tissue Injury bytert-Butyl Hydroperoxide in Wistar Rats [Internet]. Vol. 2014, Oxidative Medicine and Cellular Longevity. 2014. p. 1–9. Available from: http://dx.doi.org/10.1155/2014/716832
20. Rahman MM, Islam MB, Biswas M, Khurshid Alam AHM. In vitro antioxidant and free radical scavenging activity of different parts of Tabebuia pallida growing in Bangladesh. BMC Res Notes. 2015 Oct 30;8:621.
21. Gowder SJT. Basic Principles and Clinical Significance of Oxidative Stress. BoD – Books on Demand; 2015. 330 p.
22. Gadoth N, Göbel HH. Oxidative Stress and Free Radical Damage in Neurology. Springer Science & Business Media; 2010. 323 p.
23. Joshy R, Sridevi G, Selvaraj J, Preetha S. In vitro Antioxidant Properties of Various Extracts of Andrographis Echioides [Internet]. Journal of Pharmaceutical Research International. 2021. p. 404–11. Available from: http://dx.doi.org/10.9734/jpri/2021/v33i61a35677
24. Firdhouse MJ, Jannathul Firdhouse M, Lalitha P. Biosynthesis of Silver Nanoparticles and Its Applications [Internet]. Vol. 2015, Journal of Nanotechnology. 2015. p. 1–18. Available from: http://dx.doi.org/10.1155/2015/829526
25. Joubert E, Jolley B, Koch IS, Muller M, Van der Rijst M, de Beer D. Major production areas of rooibos ( Aspalathus linearis ) deliver herbal tea of similar phenolic and phenylpropenoic acid glucoside content [Internet]. Vol. 103, South African Journal of Botany. 2016. p. 162–9. Available from: http://dx.doi.org/10.1016/j.sajb.2015.08.015
Published
2026-03-23
How to Cite
Reenu Joshy, Dr. R.V. Geetha, & Dr Rajesh Kumar. (2026). Red tea and ginger formulation mediated silver nanoparticles and its antioxidant activity. Revista Electronica De Veterinaria, 599-603. https://doi.org/10.69980/redvet.vi.2368
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