Screening Of Bioactive Properties In Brown Green Algae Chloroform Extracts From Sargassum Muticum Seaweed
Abstract
Sargassum muticum, a brown-green macroalga, is known for its rich content of secondary metabolites with potential pharmacological applications. This study aimed to screen the bioactive properties of chloroform extracts derived from Sargassum muticum seaweed. The extract was subjected to preliminary phytochemical screening and evaluated for its antimicrobial and antioxidant activities. Results revealed the presence of bioactive compounds such as terpenoids, sterols, and phenolic derivatives. The extract demonstrated notable antimicrobial activity, particularly against Gram-positive bacteria, and exhibited moderate free radical scavenging ability, indicating the presence of lipophilic antioxidant compounds. These findings suggest that Sargassum muticum chloroform extracts hold promise as a natural source of therapeutic agents. Further studies are required to isolate and characterize individual compounds and assess their efficacy through in vivo models.
References
2. Kon K, Rai M. Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches. Academic Press; 2016. 436 p.
3. Pereira L. Characterization of Bioactive Components in Edible Algae. MDPI; 2020. 226 p.
4. Garcia-Vaquero M, Ummat V, Tiwari B, Rajauria G. Exploring Ultrasound, Microwave and Ultrasound-Microwave Assisted Extraction Technologies to Increase the Extraction of Bioactive Compounds and Antioxidants from Brown Macroalgae. Mar Drugs [Internet]. 2020 Mar 20;18(3). Available from: http://dx.doi.org/10.3390/md18030172
5. Dominguez H. Functional Ingredients from Algae for Foods and Nutraceuticals. Elsevier; 2013. 768 p.
6. Kim SK. Handbook of Marine Macroalgae: Biotechnology and Applied Phycology. John Wiley & Sons; 2011. 608 p.
7. Ford L, Stratakos AC, Theodoridou K, Dick JTA, Sheldrake GN, Linton M, et al. Polyphenols from Brown Seaweeds as a Potential Antimicrobial Agent in Animal Feeds. ACS Omega. 2020 Apr 28;5(16):9093–103.
8. Buedenbender L, Astone FA, Tasdemir D. Bioactive Molecular Networking for Mapping the Antimicrobial Constituents of the Baltic Brown Alga. Mar Drugs [Internet]. 2020 Jun 13;18(6). Available from: http://dx.doi.org/10.3390/md18060311
9. Food and Agriculture Organization of the United Nations. The global status of seaweed production, trade and utilization: FAO GLOBEFISH RESEARCH PROGRAMME VOL. 124. Food & Agriculture Org.; 2018. 124 p.
10. Rajauria G. In-Vitro Antioxidant Properties of Lipophilic Antioxidant Compounds from 3 Brown Seaweed. Antioxidants (Basel) [Internet]. 2019 Nov 28;8(12). Available from: http://dx.doi.org/10.3390/antiox8120596

