Green Synthesis and Functionalization of Silver Nanoparticles and Their Biological Applications Using Tinospora cordifolia Extract

Leela Chaudhary; Chirag Makvana

doi:10.69980/redvet.v25i1.2139

Leela Chaudhary
Chirag Makvana

DOI: https://doi.org/10.69980/redvet.v25i1.2139

Keywords: Tinospora cordifolia, Green synthesis, Silver nanoparticles, PVP functionalization, Biological activity

Abstract

Nanotechnology has revolutionized various industries, with silver nanoparticles (AgNPs) being particularly significant due to their biocompatibility and versatile applications. Traditional synthesis methods for AgNPs often involve harsh chemicals, raising concerns about environmental sustainability. Using whole plant extract from Tinospora cordifolia as a reducing agent, this work investigates the green synthesis of AgNPs, which provides a more environmentally friendly technique. The plant extract's abundant phyto-constituents, such as phenolic acids and flavonoids, stabilize the nanoparticles in addition to lowering the silver ions. To further improve these AgNPs' stability and biocompatibility, we functionalized them using polyvinyl pyrrolidone (PVP). The effective synthesis and functionalization of the produced PVP-b-AgNPs were confirmed by characterization utilizing FTIR, HR-TEM, XRD, and UV-Vis spectroscopy. Biological evaluations revealed that PVP-b-AgNPs exhibit antimicrobial activities compared to unfunctionalized b-AgNPs. These findings highlight the potential of T. cordifolia leaf extract in the sustainable synthesis of functionalized AgNPs, providing a scalable, eco-friendly alternative for applications in healthcare and other industries.

Author Biographies

Leela Chaudhary

Department of Chemistry, Faculty of Science, Gokul Global University, Sidhpur, Gujarat, India-384151

Chirag Makvana

Department of Chemistry, Faculty of Science, Gokul Global University, Sidhpur, Gujarat, India-384151

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