Preliminary Phytochemical and Antibacterial studies of Combretum ovalifolium Roxb.
Abstract
Objective: The present study aims were recognized for Pharmacological analysis and phytochemical screening of the medicinal plant Combretum ovalifolium Roxb.
Methods: As a portion of the pharmacognostic study the transverse section of the leaf was investigational and Histochemical localization studies were also done. The dried leaf powder was subjected to solvent extraction for preliminary secondary metabolites examination and a fluorescence study was done with the leaf powder.
Results: Phytochemical screening of Combretum ovalifolium Roxb. revealed the presence of steroids, triterpenoids, reducing sugars, sugars, alkaloids, phenolic compounds, flavonoids, catechins, saponins, tannins, and amino acids. Antibacterial activity was observed against six bacterial strains: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus cereus, Enterococcus aerogenes, and Staphylococcus aureus. Ethyl alcohol extracts from the leaf showed broad-spectrum activity, while stem, root, and bark extracts exhibited selective inhibition against various bacteria. These results support the potential use of Combretum ovalifolium as a natural antibacterial agent
Conclusion: This study will support the authentication and standardization of the plant Combretum ovalifolium. The present discoveries of this study show that the Combretum ovalifoliuml eaves have the great latent to act as a source of positive drugs because of the presence of a diversity of secondary metabolites such as alkaloids, flavonoids, phenol, terpenoids, saponin, and carbohydrates. These phytoconstituents may act as a source of pharmacologically dynamic agents and also natural antioxidants.
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