Development and validation of the UV-Spectrophotometric method for determination of Diaveridine in bulk and in formulation.
Abstract
Background: The aim was the study to develop a technique and validate it in a basic, financially effective UV spectrophotometry strategy for the estimation of Diaveridine in bulk and pharmaceutical dosage form according to ICH rules.
Results: The λmax of Diaveridine in 0.1N HCl was viewed in 275nm. The drug follows linearity in the fixation range 5-40µg/ml with corelation coefficient value of 0.999. The proposed technique was applied to drug formulation and percent measure of drug assessed was 92.91% and was viewed as to be in good agreement with the label claim . The accuracy was checked by recovery performed at 3 unique levels i.e. 80,100,120. The percent% recovery was viewed as in the scope of 99.12-99.84. The precision of strategy is depicted by low worth of % RSD (<2).
Conclusion: In this study 0.1N HCl picked on the grounds that it was a fast device for routine examination of Diaveridine in mass and drug dose structure.
References
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