Molecular Epidemiology Of Escherichia Coli Strains In Urinary Tract Infections: Virulence Factors And Antibiotic Resistance Patterns

  • Mrs. Mamta Patel
  • Dr. Madhurendra Singh Rajput
  • Dr. Navdeep
Keywords: Escherichia coli, urinary tract infections, virulence factors, antibiotic resistance, ESBL, multidrug resistance, CTX-M gene.

Abstract

Urinary tract infections (UTIs) are a significant clinical challenge, with Escherichia coli (E. coli) being the leading causative pathogen in both community- and hospital-acquired infections. This study investigates the virulence factors and antibiotic resistance patterns of E. coli strains isolated from symptomatic and asymptomatic UTI patients. A total of 230 E. coli strains were isolated from 2483 urine samples collected over 18 months. The study identified a high prevalence of virulence factors such as hemolysin, siderophores, and cell surface hydrophobicity, particularly in symptomatic patients. Multidrug-resistant (MDR) E. coli strains, including those producing extended-spectrum β-lactamase (ESBL) enzymes, were also identified, complicating treatment strategies. The presence of the CTX-M gene in several strains further underscores the need for careful antibiotic stewardship and continuous monitoring of resistance patterns.

 

Author Biographies

Mrs. Mamta Patel

Ph.D. Scholar, Department of Microbiology, Index Medical College, Hospital & Research Center, Malwanchal University, Indore, M.P.

Dr. Madhurendra Singh Rajput

Ph.D. Supervisor & Professor, Department of Microbiology, AIMS, Malwanchal University, Indore, M.P.

Dr. Navdeep

Associate Professor, Department of Microbiology, AIMS, Dewas, M.P.

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Published
2024-10-10
How to Cite
Mrs. Mamta Patel, Dr. Madhurendra Singh Rajput, & Dr. Navdeep. (2024). Molecular Epidemiology Of Escherichia Coli Strains In Urinary Tract Infections: Virulence Factors And Antibiotic Resistance Patterns. Revista Electronica De Veterinaria, 25(1), 2268-2270. https://doi.org/10.69980/redvet.v25i1.1183
Section
Articles