Characterizing the Virulence of Staphylococcus Aureus Isolates from Wounds: An Experimental Approach

  • Krishana Kumar Sharma Professor, College of Pharmacy, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India
  • Uzma Noor Shah Assistant Professor, Department of Life Science, School of Sciences, JAIN (Deemed-to-be University), Karnataka, India
  • Vinay Kumar H. K. Associate Professor, Department of Ayurveda, Sanskriti University, Mathura, Uttar Pradesh, India
Keywords: Wound, Disease, Enzyme, Virulence, Isolates

Abstract

In consequence of the feared superbug Methicillin-resistant Staphylococcus aureus (MRSA), people are gravely at risk for major health issues. The severity of an infection is influenced by the existence of virulence factors and medication resistance. The two most drug-resistant and virulent MRSA isolates that best exhibit the early characteristics of intestinal adhesion were chosen for this investigation in an effort to designate them for potential future using postbiotics and probiotics as antagonists to treat MRSA infections. The bacterial agent's level of pathogenicity towards the organism—i.e., its capacity to wreak disease is referred to as virulence. The virulence factors offer the virus certain qualities that allow it to fight the host's natural defences and so produce illness. The development of diverse enzymes, antibiotic resistance, and bacterial toxins are the most crucial of these elements since they all aid the pathogen's ability to adapt to varied situations. The results of the virulence factor assays revealed that each of the 50 MRSA isolates developed biofilm and hemolysin enzyme type beta and coloured blue in Gramme stain.

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Published
2023-07-10
How to Cite
Sharma, K. K., Shah, U. N., & H. K., V. K. (2023). Characterizing the Virulence of Staphylococcus Aureus Isolates from Wounds: An Experimental Approach. Revista Electronica De Veterinaria, 24(2), 523 - 534. Retrieved from https://www.veterinaria.org/index.php/REDVET/article/view/366
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Articles