Pasteurella Multocida Strains collected from Lung Infections in Bovines: a comparative study
Abstract
In the global intensive beef industry, bovine respiratory disease (BRD) is the main factor contributing to significant economic losses. In addition to several risk factors, the development of the disease may also be influenced by Pasteurella multocida, which is thought to be a secondary pathogen. An indication that some swine pneumonia strains may be more virulent than others is the discovery of a few clones in earlier studies on these strains connected to clinical illness. The BRD may have a relationship, but nothing is known about the makeup of the P. multocida populations in the herds. As a result, researchers decided on either phenotypic or genotypic Characterization of strains isolated from respiratory illness-infected calves in 31 different packs in Hungary. Two dominant strain types were found, according to the data. They could be recognized by their capacity to ferment trehalose and their activity as Molecular fingerprints of a-glucosidase obtained using ERIC and M13-PCR. They shared the same taxonomic origin (P. multocida subsp. multocida) and showed minimal phenotypic variation. Even after comparing them to strains recovered from healthy patients, the strain types' independent incidence and place of origin may be indicators of their significance in the illness.
References
Islam, E.A., Fegan, J.E., Tefera, T.A., Curran, D.M., Waeckerlin, R.C., Ng, D., Ahn, S.K., Lai, C.H.R., Nguyen, Q.H., Shah, M. and Tesfaw, L., 2023. Reverse vaccinology-based identification of a novel surface lipoprotein that is an effective vaccine antigen against bovine infections caused by Pasteurella multocida. PLoS Pathogens, 19(3), p.e1011249.
HACIOĞLU, İ.K., COŞKUN, N., YELKEN, S.D., Sevinc, S. and Alkan, F., 2019. Phylogenetic analysis of bovine respiratory syncytial virus from calves with respiratory disorders. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 25(2).
Deresse, G., Gelaye, E., Abayneh, T., Birhanu, K., Zewdie, G., Tesfaw, L., Getachew, B., Legesse, A., Akalu, M. and Gosaye, B., 2022. Molecular detection and genotyping of P. multocida, M. hemolytic, and B. trehalosi isolates targeting the virulence-associated genes from Ethiopian cattle and sheep. Journal of Genetic Engineering and Biotechnology Research, 4(3), pp.399-409.
Hashem, Y.M., Mousa, W.S., Abdeen, E.E., Abdelkhalek, H.M., Nooruzzaman, M., El-Askary, A., Ismail, K.A., Megahed, A.M., Abdeen, A., Soliman, E.A. and Wareth, G., 2022. Prevalence and molecular characterization of Mycoplasma species, Pasteurella multocida, and Staphylococcus aureus isolated from calves with respiratory manifestations. Animals, 12(3), p.312.
Xiao, J., Li, Y., Hu, Z., Zhang, Y., Chang, Y.F., Zhou, Q., Yan, Z., Zhang, X., Chen, L., Li, W. and Xie, Z., 2021. Characterization of Pasteurella multocida isolated from ducks in China from 2017 to 2019—microbial pathogenesis, 160, p.105196.
Bourély, C., Cazeau, G., Jouy, E., Haenni, M., Madec, J.Y., Jarrige, N., Leblond, A. and Gay, E., 2019. Antimicrobial resistance of Pasteurella multocida isolated from diseased food-producing animals and pets. Veterinary microbiology, 235, pp.280-284.
Alhamami, T., Chowdhury, P.R., Venter, H., Veltman, T., Truswell, A., Abraham, S., Sapula, S.A., Carr, M., Djordjevic, S.P. and Trott, D.J., 2023. Genomic profiling of Pasteurella multocida isolated from feedlot cases of bovine respiratory disease—Veterinary Microbiology, 283, p.109773.
He, F., Zhao, Z., Wu, X., Duan, L., Li, N., Fang, R., Li, P. and Peng, Y., 2021. Transcriptomic Analysis of High-and Low-Virulence Bovine Pasteurella multocida in vitro and in vivo. Frontiers in Veterinary Science, 8, p.616774.
SAKMANOĞLU, A., Uslu, A., Sayin, Z., Karyeyen, Y., GÖLEN, G.S., İLBAN, A., Padron-Perez, B., Tekindal, M.A. and ERGANİŞ, O., 2021. Investigation of the nontypical Pasteurella multocida strains obtained from multiple sources, regions, and times: an unexpected increase was detected. Turkish Journal of Veterinary & Animal Sciences, 45(5), pp.814-824.
Vu-Khac, H., Trinh, T.H., Nguyen, T.G., Nguyen, X.T. and Nguyen, T.T., 2020. Prevalence of virulence factor, antibiotic resistance, and serotype genes of Pasteurella multocida strains isolated from pigs in Vietnam. Veterinary World, 13(5), p.896.
Wang, J., Sang, L., Sun, S., Chen, Y., Chen, D. and Xie, X., 2019. Characterization of Pasteurella multocida isolated from dead rabbits with respiratory disease in Fujian, China. BMC Veterinary Research, 15(1), pp.1-6.
Tabatabaei, M., Janparvar, A. and Motamedifar, M., 2023. Genotypic evaluation of Pasteurella multocida isolated from cattle and sheep by pulsed-field gel electrophoresis. In Veterinary Research Forum (Vol. 14, No. 4, p. 213). Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Su, A., Tong, J., Fu, Y., Müller, S., Weldearegay, Y.B., Becher, P., Valentin-Weigand, P., Meens, J. and Herrler, G., 2020. Infection of bovine well-differentiated airway epithelial cells by Pasteurella multocida: actions and counteractions in the bacteria–host interactions. Veterinary research, 51(1), pp.1-11.
Cheng, Y., Wang, K., Lin, L., Zhao, X., Pan, Z. and Zhou, Z., 2020. Differences in pathogenicity and virulence-associated gene expression among Pasteurella multocida strains with high and low virulence in a lung tissue model. Microbial pathogenesis, 140, p.103911.
Klima, C.L., Holman, D.B., Cook, S.R., Conrad, C.C., Ralston, B.J., Allan, N., Anholt, R.M., Niu, Y.D., Stanford, K., Hannon, S.J. and Booker, C.W., 2020. Multidrug resistance in Pasteurellaceae associated with bovine respiratory disease mortalities in North America from 2011 to 2016. Frontiers in Microbiology, 11, p.606438.
