A Research on a Few Oral Hypoglycemic Medications to Stop the Growth of Diabetes Problems in Lab Animals

Abstract

Hyperglycemia is the defining feature of diabetes mellitus (also known as DM), which is a persistent metabolic condition. A deficiency in insulin production (type I) or insulin secretion (type II), together with resistance to the effect of insulin, or a combination of both of these variables, can lead to this syndrome. It is a condition that affects people of all ages, both sexes, and all races equally all over the world. It is a disorder that necessitates the medication-based careful management of one's glucose levels. A dangerously high level of elevated blood glucose (hyperglycemia) can lead to diabetic ketoacidosis, which in turn can cause coma and ultimately death. In a similar vein, low blood glucose, also known as hypoglycemia, can result in a coma and ultimately death. Because of this, it is necessary for the drugs to carefully manage the patient's blood glucose levels. [Cerveny JD et al., 1998] found that people with type II diabetes were more prevalent than those with type I diabetes. Insulin is helpful for diabetics who have type I diabetes. Gliclazide is one of the most commonly prescribed drugs in the category of sulfonylureas, which medications are considered to be the most effective in treating type II diabetes? The medicine Gliclazide served as the benchmark in this particular investigation. Chronic diabetes, if uncontrolled, can lead to a number of consequences, including cardiac difficulties such as angina, hypertension, cardiac dysrhythmias, and renal failure [Cerveny JD et al., 1998]. These complications are the major causes of death in chronic diabetes [Cerveny JD et al., 1998]. [Cerveny JD et al., 1998] The development of various problems, including heart issues such as angina, hypertension, and cardiac dysrhythmia, can be attributed to the presence of diabetes that is chronic.