Molecular Interaction between CTAB with NSAIDs (IBFN) by using Tensiometry, Viscometry, FTIR, and 1H NMR Techniques

  • Rashmita Khuntia
  • Prashant Mundeja
Keywords: Nonsteroidal anti-inflammatory [IBFN], CMC, surfactant, FTIR, and 1H NMR.

Abstract

Cetyltrimethylammonium bromide (CTAB), a cationic surfactant, has been interacted with Ibuprofen drug characterized by 1HNMR and FTIR spectroscopictechniques in the solid state. The surface tension method was used to calculate the values of the critical micelle concentration (CMC). Viscosity properties of the mixed system are followed by viscosity techniques. Interaction between anionic surfactants and drugs. These artificially produced surfactants are effective in raising the solubility and bioavailability of drug molecules. Additional screening was done on surfactants to check for antibacterial and antifungal properties. Parameters of the interface, like the maximum concentration of surface excess (Γmax), A molecule's smallest area (Amin), π cmc, and the adsorption efficiency (pC20), were determined.

 

Author Biographies

Rashmita Khuntia

School of Sciences, MATS University, Raipur, Chhattisgarh, India

 

Prashant Mundeja

School of Sciences, MATS University, Raipur, Chhattisgarh, India

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How to Cite
Rashmita Khuntia, & Prashant Mundeja. (1). Molecular Interaction between CTAB with NSAIDs (IBFN) by using Tensiometry, Viscometry, FTIR, and 1H NMR Techniques. Revista Electronica De Veterinaria, 25(2), 2631-2639. https://doi.org/10.69980/redvet.v25i2.2364