Evaluation of Diuretic Activity of Ethanolic Extract of Gracilaria salicornia on Mice

B. Shivananthini; S. Beulah Jerlin

doi:10.69980/redvet.v25i2.1965

B. Shivananthini
S. Beulah Jerlin

DOI: https://doi.org/10.69980/redvet.v25i2.1965

Keywords: Diuretic, Gracilaria salicornia, Wistar albino mice, electrolytes

Abstract

The present study was aimed to explore the diuretic activity of the ethanolic extract of Gracilaria salicornia (C. Agardh) EY Dawson collected from Mandapam, Ramanathapuram district, Tamil Nadu on albino mice. The dried and powdered Gracilaria salicornia was extracted in ethanol to estimate the diuretic activity. The result showed significant diuretic activity in the ethanolic extract of Gracilaria salicornia (C. Agardh) EY Dawson with increased the total urinary volume and urinary electrolyte excretion, when compared to control. 400 mg/kg dose of ethanolic extract of Gracilaria salicornia showed higher Na⁺, K⁺and Cl^-excretion than the 200 mg/kg dose of ethanolic extract. The study concludes that the ethanolic extract of Gracilaria salicornia (C. Agardh) E.Y. Dawson has potential diuretic activity.

Author Biographies

B. Shivananthini

Research Scholar (Reg. No. 21211282262009), Department of Botany, St. Mary’s College (Autonomous), Thoothukudi- 628 001, Affiliated to Manonmaniam Sundaranar University, Abishekapatti, Tamil Nadu – 627 012.

S. Beulah Jerlin

Assistant Professor, Department of Botany, St. Mary’s College (Autonomous), Thoothukudi- 628 001.

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