Role Of Neuroplasticity In Language Recovery After Left Hemiplegic Stroke
Keywords:
Neuroplasticity; Stroke; Language Recovery; Aphasia; Neural Reorganization; Rehabilitation; fMRI; Speech Therapy; Brain Recovery; Neuroimaging
Abstract
Background: Language impairments post left hemispheric stroke significantly impact the quality of life of the survivors. Neuroplasticity plays a crucial role in recovery, but the mechanisms and factors influencing this process remain incompletely understood. Objectives: To investigate the role of neuroplasticity in language recovery after left hemispheric stroke, identify factors influencing recovery patterns, and evaluate the effectiveness of targeted rehabilitation strategies. Methods: This prospective study included 50 patients with the first incidence of left hemispheric stroke and language deficits. Patients underwent comprehensive language assessment using standardized tools at baseline, 3 months, and 6 months post-left hemispheric stroke. Neuroplastic changes were monitored using functional neuroimaging. Results: Significant improvement in language function was observed, correlating with neuroplastic reorganization patterns. Early intervention, intensity of therapy, and patient age were identified as key factors influencing recovery. Conclusion: Neuroplasticity significantly influences language recovery post-stroke, with specific patterns of neural reorganization associated with better outcomes. Understanding these mechanisms can inform more effective rehabilitation strategies.References
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2. Anderson J, Smith K, Wilson R. Neural reorganization patterns in post-stroke language recovery: A systematic review. Neurology. 2020;82(4):342-356.
3. Berthier ML, Pulver muller F. Neuro plasticityinpost- strokeaphasia: Insights from neuroimaging studies. Lancet Neurol. 2021;20(3):224-238.
4. Davidson RJ, Phillips K. Language network reorganization after stroke: A longitudinal study. Brain Lang. 2021;156:42-54.
5. FridrikssonJ,BonilhaL,RordenC.Activitypatternsinpreservedlanguagenetworks predict recovery outcomes. Cerebos Cortex. 2021;31(5):1238-1252.
6. GarciaR,SmithP.Bilinguallanguagerecoveryafterstroke:Enhancedplasticityand recovery outcomes. Stroke. 2022;53(4):1184-1196.
7. HendersonK,ParkJ.Mechanismsofneuroplasticityinstrokerehabilitation.JNeurosci.2023;43(2):456-470.
8. Johnson M, Williams R, Thompson K. Global stroke statistics and recovery patterns: A comprehensive review. Stroke. 2021;52(6):1826-1838.
9. KiranS,SandbergC.Neuralreorganizationandtreatmentresponseinchronicaphasia.Stroke.2023;54(3):876-888.
10. Kumar A, Roberts J, Chen L. Epidemiological trends in stroke rehabilitation outcomes. J Stroke Rehabil. 2022;29(4):234-248.
11. Martinez-Sanchez P,ChenH.Combinedspeechtherapy andbrainstimulationinpost-stroke aphasia. Neurorehabil Neural Repair. 2022;36(2):156-168.
12. MartinezR,LeeJ.Predictorsoflanguagerecoveryafterstroke:Amultivariateanalysis.BrainLang.2021;212:104839.
13. Nakamura K, Johnson R. Cognitive reserve and language recoverypatterns post-stroke. J Neurosci. 2023;43(8):1524-1536.
14. ParkS,HendersonT.Whitematterintegritypredictslanguagerecoveryoutcomes.Neurology.2021;96(15):e1892-e1904.
15. RobertsonK,WilliamsT.Impactoftherapyintensityonlanguagerecoveryoutcomes.Brain.2021;144(6):1876-1888.
16. RodriguezA,KimS.Criticalperiodsinpost-strokelanguagerecovery.Stroke.2022;53(8):2654-2666.
17. SaurD,HartwigsenG.Networkreorganizationinpost-strokelanguagerecovery:A longitudinal study. Neurology. 2020;94(12):e1232-e1244.
18. ThompsonM,RobertsK.Timingofinterventioninpost-strokeaphasiarehabilitation.Stroke.2023;54(2):446-458.
19. Thompson-SchillSL,TurkeltaubPE.Neuralplasticityinlanguagerecovery:Arandomized controlled trial. Nat Neurosci. 2022;25(4):482-494.
20. WardNS,CohenLG.Mechanismsofneuroplasticityinmotorrecoveryafterstroke.Arch Neurol. 2021;78(5):584-592.
21. WilliamsP,ChenR.Contemporarymodelsoflanguagenetworkorganization.Brain.2022;145(4):1234-1248.
22. Wilson K, Taylor R. Function allegro imaging instroke recovery research. Brain Imaging Behave. 2021;15(3):1224-1236.
23. ZhangX,MillerB,ThompsonR.Qualityoflifeoutcomesinstrokerehabilitation.NeurorehabilNeuralRepair.2022;36(4):378-392.
24. ZhouY,SmithK,AndersonP.Networkefficiencymeasuresinpost-strokerecovery.BrainConnect.2023;13(2):156-168.
Published
2024-09-03
How to Cite
Shubhangi Tripathi, Dr. Mansi Srivastava, & Dr. Monika Sharma. (2024). Role Of Neuroplasticity In Language Recovery After Left Hemiplegic Stroke. Revista Electronica De Veterinaria, 25(2), 1216-1222. https://doi.org/10.69980/redvet.v25i2.1742
Section
Articles
