Acoustic Analysis of Clindamycin Aqueous Solution at Various Temperatures and different Concentrations

  • Shrirame S.H
  • Dhote A.B
Keywords: Ultrasonic velocity, Clindamycin, concentration, temperature, molecular interactions

Abstract

These days, knowledge of interactions between molecules in solution is mostly dependent on ultrasonic velocity. Drugs are substances that have been utilized to treat medical conditions. Clindamycin is one medication that fights malaria. We measured the density, viscosity, and ultrasonic velocity of the aqueous solution at different temperatures and concentrations. The thermodynamic properties, such as Relative association Specific Relaxation time, were calculated using the experiment data. This assists in the predicting of chemical interactions.

Author Biographies

Shrirame S.H

Chemistry Department, N S Sceience and Arts College, Bhadrawati Dist- Chandrapur.

Dhote A.B

Chemistry Department, N S Sceience and Arts College, Bhadrawati Dist- Chandrapur.

References

1. Zwiebel, William J., and John S. Pellerito. Introduction to vascular ultrasonography. Philadelphia: Elsevier Saunders, 2005.
2. Tunn, R., et al. "Updated recommendations on ultrasonography in urogynecology." International Urogynecology Journal 16 (2005): 236-241.
3. Lea, S. C., Gabriel Landini, and A. D. Walmsley. "Assessing the vibrations of dental ultrasonic scalers." Journal of sound and vibration 271.3-5 (2004): 1113-1120.
4. Chandrapala, Jayani, et al. "Ultrasonics in food processing." Ultrasonics sonochemistry 19.5 (2012): 975-983.
5. Bhaskaracharya, Raman Kumar, Sandra Kentish, and Muthupandian Ashokkumar. "Selected applications of ultrasonics in food processing." Food Engineering Reviews 1 (2009): 31-49.
6. Naidu, Haripriya, Ozan Kahraman, and Hao Feng. "Novel applications of ultrasonic atomization in the manufacturing of fine chemicals, pharmaceuticals, and medical devices." Ultrasonics Sonochemistry 86 (2022): 105984.
7. Freitas, Sergio, et al. "Continuous contact-and contamination-free ultrasonic emulsification—a useful tool for pharmaceutical development and production." Ultrasonics sonochemistry 13.1 (2006): 76-85.
8. Ali, Anwar, and A. K. Nain. "Ultrasonic study of molecular interaction in binary liquid mixtures at 30 C." Pramana 58 (2002): 695-701.
9. Light, Donald W., and Rebecca Warburton. "Demythologizing the high costs of pharmaceutical research." BioSocieties 6 (2011): 34-50.
10. Agatonovic-Kustrin, S., and Rosemary Beresford. "Basic concepts of artificial neural network (ANN) modeling and its application in pharmaceutical research." Journal of pharmaceutical and biomedical analysis 22.5 (2000): 717-727.
11. Marin, Alexander, Md Muniruzzaman, and Natalya Rapoport. "Mechanism of the ultrasonic activation of micellar drug delivery." Journal of controlled release 75.1-2 (2001): 69-81.
12. Husseini, Ghaleb A., and William G. Pitt. "Ultrasonic-activated micellar drug delivery for cancer treatment." Journal of pharmaceutical sciences 98.3 (2009): 795-811.
13. Phillips, I. A. N. "Clinical uses and control of rifampicin and clindamycin." Journal of Clinical Pathology 24.5 (1971): 410.
14. Armillei, Maria K., et al. "Scientific rationale and clinical basis for clindamycin use in the treatment of dermatologic disease." Antibiotics 13.3 (2024): 270.
15. Pool, Christopher, et al. "Increased surgical site infection rates following clindamycin use in head and neck free tissue transfer." Otolaryngology–Head and Neck Surgery 154.2 (2016): 272-278.
16. Rao, B. P. C., et al. "New methodology for precise ultrasonic velocity measurement and its applications." J. Pure Appl. Ultrason 15 (1993): 53-59.
17. Lu, Yinghui, and Jennifer E. Michaels. "A methodology for structural health monitoring with diffuse ultrasonic waves in the presence of temperature variations." Ultrasonics 43.9 (2005): 717-731.
18. Hancu, Gabriel & Papp, Lajos & Blanka, Székely & Hajnal, Kelemen. (2022). The Use of Antibiotics as Chiral Selectors in Capillary Electrophoresis: A Review. Molecules. 27. 3601. 10.3390/molecules27113601.
19. Lagemann, R. T., D. R. McMillan Jr, and W. E. Woolf. "Temperature variation of ultrasonic velocity in liquids." The Journal of Chemical Physics 17.4 (1949): 369-373.
20. Prabakar, S., and K. Rajagopal. "Study of molecular interactions in aprotic-aprotic binary mixtures through ultrasonic measurements." JOURNAL OF PURE AND APPLIED ULTRASONICS 27.2/3 (2005): 41.
21. Litovitz, Theodore A. "Theory of ultrasonic thermal relaxation times in liquids." The Journal of Chemical Physics 26.3 (1957): 469-473.
22. Giratkar, V. A., R. B. Lanjewar, and S. M. Gadegone. "Ultrasonic studies of amino acid in aqueous salt solution at different temperatures." Int. J. Res. Biosci., Agri. Technol 5.3 (2017): 41-45.
23. Patil, K. C., and C. M. Dudhe. "Molecular interaction study of aqueous solution of an aminoglycoside antibiotic Neomycin at 298.15 to 308.15 K." Der Pharma Chemica 7.12 (2015): 219-226.
Published
2024-06-30
How to Cite
Shrirame S.H, & Dhote A.B. (2024). Acoustic Analysis of Clindamycin Aqueous Solution at Various Temperatures and different Concentrations. Revista Electronica De Veterinaria, 25(1S), 1542 - 1546. https://doi.org/10.69980/redvet.v25i1S.1308